Biomedical Translational Research Drug Design and Discovery (R.C. Sobti, Naranjan S. Dhalla)

Chen L, Morrow JK, Tran HT, Pathak SS, Du-Cuny L, Zhang S (2012) From laptop to bench top to

bedside: structure-based drug design on protein targets. Curr Pharm Des 18(9):1217–1239.

https://doi.org/10.2174/138161212799436386

Cooley P, Wallace D, Antohe B (2002) Applications of ink-jet printing technology to bio MEMS

and microﬂuidic systems. J Assoc Lab Autom 7(5):33–39. https://doi.org/10.1016/S1535-5535-

04-00214-X

Costa J, Ahluwalia A (2019) Advances and current challenges in intestinal in vitro model engineer-

ing: a digest. Front Bioeng Biotechnol 7:144. https://doi.org/10.3389/fbioe.2019.00144

Costello CM, Jia HP, Shafﬁey S, Yu JJ, Jain NK, Hackam D (2014) Synthetic small intestinal

scaffolds for improved studies of intestinal differentiation. Biotechnol Bioeng 111:1222–1232.

https://doi.org/10.1002/bit.25180

Deng J, Wei W, Chen Z, Lin B, Zhao W, Luo Y (2019) Engineered liver-on-a-chip platform to

mimic liver functions and its biomedical applications: a review. Micromachines (Basel) 10:676.

https://doi.org/10.3390/mi10100676

Derakhshanfar S, Mbeleck R, Xu K, Zhang X, Zhong W, Xing M (2018) 3D bioprinting for

biomedical devices and tissue engineering: a review of recent trends and advances. Bioact Mater

3(2):144–156. https://doi.org/10.1016/j.bioactmat.2017.11.008

Dixon CL, Richardson L, Sheller-Miller S, Saade G, Menon R (2018) A distinct mechanism of

senescence activation in amnion epithelial cells by infection, inﬂammation, and oxidative stress.

Am J Reprod Immunol 79(3). https://doi.org/10.1111/aji.12790

Doke SK, Dhawale SC (2015) Alternatives to animal testing: a review. Saudi Pharm J 23(3):

223–229. https://doi.org/10.1016/j.jsps.2013.11.002

Esch EW, Bahinski A, Huh D (2015) Organs-on-chips at the frontiers of drug discovery. Nat Rev

Drug Discov 14(4):248–260. https://doi.org/10.1038/nrd4539

Frohlich EM, Alonso JL, Borenstein JT (2013) Topographically-patterned porous membranes in a

microﬂuidic device as an in vitro model of renal reabsorptive barriers. Lab Chip 13(12):

2311–2319. https://doi.org/10.1039/C3LC50199J

Galarraga JH, Kwon MY, Burdick JA (2019) 3D bioprinting via an in-situ crosslinking technique

towards engineering cartilage tissue. Sci Rep 9:19987. https://doi.org/10.1038/s41598-019-

56117-3

Gori M, Simonelli MC, Giannitelli SM, Businar L, Trombetta M, Rainer A (2016) Investigating

nonalcoholic fatty liver disease in a liver-on-a-chip microﬂuidic device. PLoS One 11(7):

e0159729. https://doi.org/10.1371/journal.pone.0159729

Griep LM, Wolbers F, de Wagenaar B (2013) BBB on chip: microﬂuidic platform to mechanically

and biochemically modulate blood-brain barrier function. Biomed Microdevices 15(1):

145–150. https://doi.org/10.1007/s10544-012-9699-7

Gu Z, Fu J, Lin H, He Y (2020) Development of 3D bioprinting: from printing methods to

biomedical applications. Asian J Pharm Sci 15(5):529–557. https://doi.org/10.1016/j.ajps.

2019.11.003

Guido RV, Oliva G, Andricopulo AD (2011) Modern drug discovery technologies: opportunities

and challenges in lead discovery. Comb Chem High Throughput Screen 14(10):830–839.

https://doi.org/10.2174/138620711797537067

Harper AR, Topol EJ (2012) Pharmacogenomics in clinical practice and drug development. Nat

Biotechnol 30(11):1117–1124. https://doi.org/10.1038/nbt.2424

Homan K, Kolesky D, Skylar-Scott M, Herrmann J, Obuobi H, Moisan A, Lewis JA (2016)

Bioprinting of 3D convoluted renal proximal tubules on perfusable chips. Sci Rep 6:34845.

https://doi.org/10.1038/srep34845

Hughes JP, Rees S, Kalindjian SB, Philpot KL (2011) Principles of early drug discovery. Br J

Pharmacol 162(6):1239–1249. https://doi.org/10.1111/j.1476-5381.2010.01127.x

Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE (2010)

Reconstituting organ-level lung functions on a chip. Science 328(5986):1662–1668. https://

doi.org/10.1126/science.1188302

Organ-on-a-Chip: Novel In Vitro Model for Drug Discovery